Two weeks ago, researchers at the University of Washington reported that they managed to create new heart cells from human embryonic stem cells, and in doing so they successfully restored damaged heart muscles in monkeys. At the heart of the study was the researchers’ ability to inject 1 billion heart muscle cells – cardiomyocytes – derived from human embryonic stem cells, into infarcted muscle. The new heart muscle cells then penetrated the damaged heart tissue, matured, assembled into muscle fibers and began to beat in synchrony with the heart cells. Eventually, the cells fully integrated with the host heart muscle.
A remarkable study, and one that drives home the message of the importance of successful stem cell differentiation. We have all been there: poorly controlled cultures which result in low differentiation yield or poor bioassay output. And yet, researchers continue to operate with such suboptimal conditions, or seek help from inexperienced cell culture labs.
At Akron, we offer cell culture and bioassay capabilities that can help reign in some of the chaos of poorly performing cultures. From developing custom bioassays tailored to your specific application – which can include anything from growth factor characterization to cell-based protein characterization assays – through to cell line and media qualification, our cell-based bioassays and culture capabilities can eliminate uncertainties that arise when developing your own culture setup.
This can range from small, single cell line projects to extensive, multi-level characterization campaigns.