Regenerative therapies are increasingly turning to tissue engineering as a viable route to mechanically stable and biocompatible scaffolds for tissue repair. If you have been following our blog, you will have noticed that here at Akron we recognize the critical importance that the environment plays in cell culture. Indeed, it is the extracellular environment that ensures good cell adhesion, migration, proliferation, and differentiation and cell and scaffold constructs should ultimately possess good biological and mechanical function to be clinically useful for tissue replacements.
A variety of materials – primarily natural and synthetic polymers – have been used as scaffolds for tissue regeneration. Among natural biomaterials, collagen – commonly found in the extracellular matrix (ECM) in vivo – has found widespread use as a biocompatible ECM scaffold with good spatial integrity, particularly recently in osteochondral tissue engineering (Benders et al., Trends in Biotechnology, 2013, 31(3):169). Not only that, collagen films were recently successfully delivered subretinally in retinal pigment epithelial transplant therapy (Binder, S.; Br J Ophthalmol, 2011;95:441-442). Moreover, collagen can also be cross linked to improve its mechanical stability.
It does not take long to understand the importance of selecting the optimal ECM conditions for tissue culture. Akron Biotech can not only help you in your regenerative tissue engineering endeavors by delivering optimal collagen-based extracellular matrix scaffolds, but also by tailoring the scaffold specifications to meet the exact needs of your culture – from cell line optimization to media supplementation for optimal performance.
So contact us and let’s chat about your needs – we’re ready. Are you?
Samples of PCL and Collagen scaffolds available upon request, limited free samples.
We will be at ISCT NA Regional Meeting on September 8-11th in Philadelphia. On Sunday Akron Biotech will chair a session on Raw Materials and its impact in CT. We will also have a booth and Akron Biotech staff to see you there. If you need an appointment to discuss customized products or services, please email us at email@example.com or fill the form below.